Neuroscience CH16Schiz

Neuroscience CH16Schiz - Behavioral Neuroscience Ch. 16...

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Behavioral Neuroscience Ch. 16 Schizophrenia and Affective Disorders Schizophrenia Schizophrenia: serious mental disorder characterized by disordered thoughts, delusions, hallucinations and often bizarre behaviors o Positive symptoms: thought disorder (disorganized, irrational thinking); delusion (belief that is clearly in contradiction to reality-persecution, grandeur and control);hallucination (perception of a nonexistent object or event) o Negative symptoms: absence or diminution of normal behaviors; social withdrawal, lack of initiative and persistence, anhedonia (inability to experience pleasure), lack of affect o Cognitive symptoms: characterized by deficits in sustained attention, psychomotor speed, learning and memory, abstract thinking and problem solving There are several genes involved in schiz; its not wholly recessive or dominant Studies show that children of older fathers are more likely to develop schiz (mutations in spermatocytes) Dopamine hypothesis: symptoms of schizophrenia are caused by overactivity of synapses btwn dopaminergic neurons of the ventral tegmental area and in the nucleus accumbens and amygdala Chlorpromazine is an effective treatment for schiz; all schiz drugs block dopamine receptors L -DOPA, cocaine and amphetamine are all dopamine agonists
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Neuroscience CH16Schiz - Behavioral Neuroscience Ch. 16...

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