Study Guide II -- COMPLETE

Study Guide II -- COMPLETE - Jennifer Fifield Professor...

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Jennifer Fifield Professor Linda Martin-Morris Biology 100 Biology 100 -- Study Guide, Week II I. Vocabulary - Synergism, antagonism, incompatibility, additivity - Neuron, neuroglia [neuroglial cell], cell body, axon, dendrite, axon bulb - Electrical activity, resting potential, action potential - Na+ [sodium], K+ [potassium], Cl- [chloride] - Na+/K+ pump, Na+ channels, K+ channels II. Drug Combinations A. For negative drug interactions, the two terms include incompatibility and antagonism. In incompatibility, the drugs interfere with each other. In antagonism, DRUG X + DRUG Y > DRUGS X + Y. In positive drug interactions, the two terms are additivity and synergism. In additivity, DRUG X + DRUG Y = DRUGS X + Y. In synergism, DRUG X + DRUG Y < DRUGS X + Y. B. See graphs in Lecture Companion. C. An example of incompatibility is when aspirin [temporary pain reliever, heart strengthener, blood thinner] is taken with Metamucil [laxative]. This decreases absorption in the body. In antagonism, If Valium [anxiety] is taken with caffeine, there will be conflicting mechanisms because of the reaction between those two drugs. In additivity, if aspirin and methotrexate [reduce inflammation] are taken together, they attack the same symptoms, have different mechanisms, and have a double edge approach. In synergism, drugs such as alcohol and benzodiazepine [sedative] which are taken together greatly increases disinhibition.
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D. When one chooses a pill, one takes the good with the bad.
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This note was uploaded on 04/25/2008 for the course BIOL 100 taught by Professor Martin-morris during the Fall '07 term at University of Washington.

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Study Guide II -- COMPLETE - Jennifer Fifield Professor...

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