Week 2 - Amino Acids Amino acids can be grouped based on...

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Amino Acids Amino acids can be grouped based on their side chains: neutral-nonpolar neutral-polar acidic basic
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Neutral Amino Acid Side Chains: I. non-polar
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Neutral Amino Acid Side Chains: I. non-polar
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Neutral Amino Acid Side Chains: II. polar
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Charged Amino Acid Side Chains: I. acidic Compare to:
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Charged Amino Acid Side Chains: II. basic
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Ile The Chemical Structures of Amino Acids
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Formation of a Peptide Bond Peptide bond formation is a condensation reaction-water is released. Hydrolysis is the reverse reaction. The peptide bond is an amide linkage. Polypeptides have a defined orientation: from N- to C- terminus. Polymerization with the next amino acid (during protein synthesis) occurs at the C- terminus.
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The Structure of Proteins Proteins are linear polymers typically from ~100-1000 amino acid residues in length, but may be a few times larger or smaller. The average amino acid has a molecular weight (MW) of 110 daltons (Da), so most proteins have a mass in the range of ~10-100 kDa. Adjacent amino acids are covalently bonded by peptide bonds.
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Hierarchies of Protein Structure Primary structure : The linear sequence of amino acids from the N- to C-terminus. Secondary structure:
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This note was uploaded on 02/28/2008 for the course BISC 320L taught by Professor Baker,aparicio during the Fall '07 term at USC.

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Week 2 - Amino Acids Amino acids can be grouped based on...

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