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Unformatted text preview: Mutation Basics Mutationheritable change in the genetic material; a change in my RNA is not a mutation because it is not a change in the genetic material Point mutations from the DNA perspective point mutationchange that effects one nucleotide or one base pair (odds: incredibly small; happens during replication). Different kinds: Substitutions- Transition: Y(pyrimidine)-> Y (different one) or R R (more common Than transversions by far) Transversion: Y R or Y R deletionloss of genetic material 1 or more nucleotide (CCTACC CCACC). Since its deleted, the only way you could tell something was wrong was if you knew how it was supposed to read Insertionadding of 1 or more nucleotide. CCTACC CCTTACC Inversion (not point mutation) AB|CDE|FG ABEDCFG Point mutations from the polypeptide perspective (Fig below) original sequence mutated sequence same-sense (is a mutation, substitution (transistion?), same sense mutation) 5 TCT.CAA.AA A .TTT.ACG 3...
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