Module 7 - Module 7 Hardy-Weinberg The Gene Pool Evolution...

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Module 7Hardy-WeinbergThe Gene PoolEvolution is a change in the genetic makeup of a populationThe total of all the genetic (allele) variation in a population is the gene pool.Allele and genotype frequenciesIndividuals have phenotypes and genotypes; populations have distributions of phenotypes, genotypes, and allelesWe calculate these as frequenciesGenotype/Phenotype frequency= # of individuals with genotype in population/total # of individuals in populationAllele frequency= # of copies of allele in population/ total # of copies of all alleles in populationGenotype frequencies:oFrequency of genotype AA= NAA/NoFrequency of genotype Aa=NAa/NoFrequency of genotype aa+ Naa/NAllele frequencies:oP=frequency of AP=2NAA+NAa/2Noq=frequency of aq=2Naa+NAa/2NNote that for a system with two alleles, p+q always= 1Sum of the genotype frequencies also always=1Hardy- Weinberg EquilibriumHardy-Weinberg Equilibrium is a way of describing allele and genotype frequencies in a population that doesn’t change (i.e no evolution)Assumes: no mutation, no migration, no selection, infinitely large population, random matingCalculation HWEIn a population at Hardy-Weinberg Equilibrium, genotype frequencies are predictable from allelefrequencies

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