EBio - notes1 - Malar MRSA 10-23

EBio - notes1 - Malar MRSA 10-23 - Variation Inheritance...

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Unformatted text preview: Variation Inheritance Selection Genetics & Evolution Overview: Concepts Genes, dominant, recessive, heterozygote, homozygote, heterozygote advantage Malaria, Sickle cell disease, hemoglobin Staphylococcus aureus , methicillin, MRSA, antibiotics, sensitive, resistant Figs 23.13, 28.11 Wikipedia entries on sickle cell and malaria are useful resources Genetics & Evolution Overview: Genes, dominant, recessive, heterozygote, homozygote, heterozygote advantage Malaria, Sickle cell disease, hemoglobin Staphylococcus aureus , methicillin, MRSA, antibiotics, sensitive, resistant Figs 23.13, 28.11 Wikipedia entries on sickle cell and malaria are useful resources Genetics & Evolution Overview: Vocabulary & Figures Part 1: Sickle Cell Disease is caused by a mutation in hemoglobin genes Results in sickle-shaped red blood cells Cells get stuck in blood vessels, causes oxygen deprivation, organ damage Shortened life expectancy Genetics of sickle cell disease Caused by a mutation in hemoglobin (protein that binds oxygen in red blood cells) gene This is a recessive genetic disorder (not dominant) Recessive genetic disorders For full expression of disorder, require two defective genes (one from mom, one from dad) Sickle cell carrier Sickle cell Heterozygous Rr Homozygous RR rr No trait Homozygous dominant : normal, RR Heterozygous: sickle cell trait, altitude, Rr Homozygous recessive : sickle cell disease, rr Part 2: Malaria is caused by Plasmodium falciparum, Plasmodium vivax, etc....
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This note was uploaded on 02/28/2008 for the course EBIO 1210 taught by Professor Demmig-adam during the Fall '07 term at Colorado.

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EBio - notes1 - Malar MRSA 10-23 - Variation Inheritance...

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