EBio - notes4 - Gene Expression 11-15

EBio - notes4 - Gene Expression 11-15 - DNA variation leads...

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DNA variation leads to phenotypic variation DNA codes for proteins which leads to phenotypes Sequence information in DNA is transmitted to proteins in the following way: DNA to RNA to protein “The central dogma of molecular biology” DNA codes for RNA, which codes for proteins •Transcription is an enzymatic process for converting DNA to RNA •Translation is an enzymatic process for converting RNA to proteins One gene- one protein hypothesis Always some exceptions… Some proteins are composed of several polypeptides, each of which is coded for by a separate gene Therefore, one gene–one polypeptide hypothesis Some genes are never coded into protein- just to RNAs…
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Genes code for RNA, which codes for proteins One gene- one protein hypothesis DNA expression: Translation, transcription RNA polymerase The genetic code, degenerate Chapter 17, Figures 17.3, 4, 5, 7, 13, 14, CONCEPTS: 1. DNA is transcribed to mRNA 2. mRNA is translated to protein 3. The genetic code is degenerate but unambiguous
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EBio - notes4 - Gene Expression 11-15 - DNA variation leads...

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