Bio D103 Homework 3_Week 4-KEY

Bio D103 Homework 3_Week 4-KEY - Bio D103: Cell Biology...

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Bio D103: Cell Biology Dr. Salme Taagepera Winter 2009 Bio D103: Homework #3 This homework is due by 1pm Friday, January 30, 2009 to the Bio D103 EEE DropBox . In order to receive full credit, you must submit your work CORRECTLY to the proper EEE DropBox. o Please submit ONLY the answers (DO NOT submit any part of the questions) o Any work submitted late or to the wrong folder will be given half- credit. (Reminder: the 1pm class is Bio 103A , the 2pm class is Bio 103B .) Instructions for submitting to the EEE DropBox: go to EEE DropBox Bio D103 Assignment Submission Homework #3 ********* 1. Motor proteins A. Binding and hydrolysis of ATP by myosin causes a series of conformational changes in the myosin motor protein, causing it to “walk” along the actin filament. In the chart below, indicate the effect that the binding/hydrolysis of ATP has on myosin conformation. ATP state Effect on myosin No ATP bound to myosin Myosin head locked onto AF (attached) Binding of ATP Release of AF by myosin head (release) Hydrolysis of ATP, ADP and Pi remain bound Head displaced forward (cocked) Pi and ADP released Head binds next actin subunit (force-generating step)
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Bio D103: Cell Biology Dr. Salme Taagepera Winter 2009 B. There are no known motor proteins that use intermediate filaments as tracks. Why is it that the intermediate filaments cannot support motor activity?
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Bio D103 Homework 3_Week 4-KEY - Bio D103: Cell Biology...

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