old_midterm-1-questions

old_midterm-1-questions - Bio Sci 104 MIDTERM#1(Lecture 2-9...

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Bio Sci 104 MIDTERM #1 (Lecture 2-9) A. There are three versions of the exam with same questions but in different order. B. All questions have equal value. 37 questions total (3 points each). C. Number of “ * ” denotes the number of correct answers (questions 1-31). You need to mark ALL correct answers to get the credit . No penalties and no partial credits. D. It is essential that you fill out the following both on this sheet and on Scantron (bubble in your student ID). Failure to do so may result in loss of some or all credit for this exam. Your name _________________________________________________ Your student ID _____________________________________________ The version of this exam: ________ a ________( red color marks correct answers )________ **1. Discussing mitochondrial protein transport: which of the following statements are correct? a. Mitochondrial proteins are transported from trans-Golgi through vesicle fusion. b. Mitochondrial proteins are transported through the Sec61 transporter. c. HSP70 is a chaperone that helps proteins targeted to the mitochondria to fold d. Mitochondrial proteins are transported into mitochondria as they are made on the mitochondrial membrane by the ribosomes. e. Mitochondrial proteins are transported through the Tom/Tim complex. *2. How and where is the Rab-GDP complex converted to a Rab-GTP complex? **3. Based on what we discussed in class, which of the following suggest that present-day life might have evolved from an RNA-based biology? *4. What is the resolution limit of the fluorescence microscopes? **5. Discussing protein coats in vesciular transport: a. Drive budding and provide a means of distinguishing different types of vesicles b. Determine the specificity of vesicles docking to target membranes c. clathrin coatmers do not disassemble until vesicles dock to target membrane d. COPII proteins coat vesicles formed at Trans-Golgi e. clathrin proteins coat vesicles formed at Trans-Golgi **6. Nuclear transport:
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Bio Sci 104 a. is gated by nuclear pore complex b. nuclear membrane proteins first synthesized in the cytosol then transported into the nucleus c. the nuclear localization sequences (NLS) of the nucleoplasm proteins are cleaved after transport d. requires importin receptors for transporting nuceloplasm localized proteins e. binding of the Ran-GDP cause the import receptor to release their cargo
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