In class notes for November 14, 2007

In class notes for November 14, 2007 - Introduction to...

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Introduction to Biological Sciences 110a In class notes for November 14, 2007 We are talking about gene expression o Steps Transcription Bacteria Eukaryotes o RNA polymerase II TFIID and the TATA box are important Eukaryotic RNA procession of Pol II transcripts o Capping o hnRNP formation o Splicing o Polyadenylation o Transport Processing is cotrancriptional o Capping, and other things occur as RNA is being made o As RNA is made available, the processing steps occur Processing steps o Capping Carried out by a protein or and enzyme called capping enzyme This protein or enzyme adds a GTP to the 5’ end of the nascent RNA molecule The GTP is added using a odd linking The linkage is unusual, it is called a 5’- triphosphate- 5’- linkage See slide See A After the G is added you get methylation of the N7 of G So the G is “capped by a methyl group” Why does the cell have the cap?
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Introduction to Biological Sciences 110a In class notes for November 14, 2007 The function of the cap is to protect the RNA from 5’ exonucleases. So it
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In class notes for November 14, 2007 - Introduction to...

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