In class notes for November 30, 2007

In class notes for November 30, 2007 - Introduction to...

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Introduction to Biological Sciences 110a In class notes for November 30, 2007 Gene expression o Translation Elongation Termination Eukaryotes and Prokaryotes are very similar so we will talk about them together in elongation and termination Last time we talked about the formation of the peptide bond o We have ribosome going 3’ to 5’ In the P site there is a peptidyl tRNA and there are n amino acids attached to it At the A site there is n+1 E is the exit site Elongation cycle o We will start at the peptidyl tRNA n in the P-site tRNA n-1 in E site (or already ejected) o EF-Tn GTP Delievers the next aminoacyltRNA n+1 to the A site The hydrolysis of the GTP is used to insure the appropriate codon-anticodon interactions There is a whole the tRNAs can enter to get to the A site o Peptidyl transferase catalizes bind formation 3’ end of the tRNA n which is now uncharged is pushed into the E site, but the bottom of it is still in the P site. The 3’ end of the tRNA
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This note was uploaded on 02/22/2009 for the course BSCI 110A taught by Professor Broadie/patton during the Fall '08 term at Vanderbilt.

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In class notes for November 30, 2007 - Introduction to...

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