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Unformatted text preview: BME 210 2009 Spring Semester Homework 2 Receptor-Ligand Kinetics (100 points) Due Monday Feb 23, 2008 (At the start of class) An important goal of biomedical engineering is to understand cellular behavior in terms of the cells molecular processes. Central to this understanding is knowledge of how cell membrane- bound receptors interact with ligands to direct cellular communication, proliferation and protein synthesis (intracellular signaling). Moreover, receptors and their ligands ( e.g. , growth factors, hormones, neurotransmitters) are ideal candidates for molecular manipulation, thereby allowing for the modification of receptor-ligand association and dissociation rates and therefore intracellular signaling activities. This homework assignment will explore the kinetics of the following receptor-ligand interaction: The diagram represents a simplified receptor-ligand model for the N-methly-D-aspartate (NMDA) receptor for the excitatory neurotransmitter glutamate, the primary neurotransmitter in...
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This note was uploaded on 02/23/2009 for the course BME 210 taught by Professor D'argenio during the Spring '07 term at USC.
- Spring '07
- Biomedical Engineering