bionb 222 final - 7) Adderall (amphetamine) was originally...

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7) Adderall (amphetamine) was originally marketed for treatment of ADHD, but it is used more and more as a study aid for college students, who claim that it makes studying more interesting. Adderall has the same molecular actions as methamphetamine and cocaine in the brain. a. Based on your knowledge of psychostimulants, describe how Adderall might enhance attention for studying. b. Explain, in physiological terms why you should not continue to take high doses of Adderall for long times. Molecular actions of methamphetamine and cocaine: (psychostimulants) Adderall, an amphetamine used to treat ADHD, has the same molecular actions as certain highly addictive psychostimulants, such as methamphetamine and cocaine. Both methamphetamine and cocaine are known to elevate mood, induce euphoria and a strong sense of confidence, increase alertness, reduce fatigue and appetite by presynaptic action. The main target of these stimulants is the presynaptic nerve terminal transporter for dopamine (DAT). By blocking these transporters dopamine is recycled back into the nerve terminal for reuse and its action at the synapse is prolonged. Additionally, methamphetamine causes the transporter to run backwards so that the dopamine in the terminal cytoplasm is released into the synaptic cleft in a vesicle independent manner. how? - enhance dopamine levels in the brain 1. vesicles help release neurotransmitters in a set dose (1 quanta). releasing the dopamine in an indep manner will cause way more to be
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bionb 222 final - 7) Adderall (amphetamine) was originally...

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