PSL 201 Lecture 8 - PSL 201 > Mavrogiannis > Renal Lecture...

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PSL 201 > Mavrogiannis > Renal Lecture 3 Re-absorption Passive diffusion Active transport Active/Passive reabsorption of solutes- using ATP or chemical gradient active transport carriers on basolateral membrane. LUMEN TUBULAR CELL INTERSTITIAL FLUID PERITUBULAR CAPILLARY Barriers: Endothelial wall of capillary and tubular wall of tubule. Active/passive/ diffusion Water reabsorption- Difference in osmolarity when solutes absorbed the osmolarity of the tubular cell decreases and the osmolarity of plasma decreases. Transport Maximum= GFR * renal threashold Eg. Glucose- substances that are 100% of filtered reabsorbed. When too much of the substance is present in the plasma the protein carriers become saturated and some found in urine – Renal threshold. Glucose uses Na + (cotransport), K + (contratransport) gradients to transport glucose into the apical membrane through the basolateral membrane into the plasma ( glomerulus) Secretion Like reabsorption but in the reverse direction. Substance move from plasma into
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