PSL 201 Lecture 9 - PSL 201 > Mavrogiannis > Renal...

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PSL 201 > Mavrogiannis > Renal Lecture 4 Homeostasis must be kept in balance—what is produced by the body must be eliminated Plasma Composition: The kidney control volume by control solute and water content. Solute and water content of the plasma is affected by materials into and out of the body. The plasma can gain/ lose material from the GI tract or lumen of renal tubule or sweating or haemorrhage. Volume of plasma determined by water content and solutes effect the osmolarity that causes shifts in fluids. HYPOOSMOTIC – cells shrinks HYPEROSMOTIC- cells bursts. Water absorption in PCT - most of the sodium reabsorbed in the PCT therefore medullar osmotic grad. responsible for water reabsorption. The descending limb is permeable to water the thick ascending limb has transports for ions like Na, Cl, K. Therefore the osmolarity increases going down the loop of henle. Creates the counter current multiplier which the water and the ions move in diff direction. Counter current gradient-How can the kidney change the concentration of urine?
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This note was uploaded on 02/25/2009 for the course PSL 201 taught by Professor Wojtowicz during the Spring '08 term at University of Toronto- Toronto.

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PSL 201 Lecture 9 - PSL 201 > Mavrogiannis > Renal...

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