Prenatal testing for genetic disease

Prenatal testing for genetic disease - Prenatal testing for...

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Prenatal testing for genetic disease Amniocentesis o Sample of fluid that surrounds the fetus (very complex) o Tricked into dividing Chorionic Villus sampling Transgenic Organisms o Higher plants and animals into which foreign genes have been transferred Transgenic Mice (Models for Biomedical Research) Gene therapy o Mostly based on techniques used to develop transgenic animals – but usually only have to get genes into certain cells o Various techniques are used – e.g. using viruses as vectors o Very difficult – research is moving slowly Agriculture – transgenic animals Agriculture – transgenic plants Safety concerns o Specific safety guidelines for using recombinant DNA technology o Concerns about introduction of transgenic plants and animals into the natural environment HUMAN GENETICS Sickle Cell Anemia o Autosomal recessive o Abnormal beta chains in hemoglobin – cause red blood cells to assume “sickled” shape o 1/10 to 1/12 Americans of black African ancestry are heterozygous (Ss)
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This note was uploaded on 02/28/2009 for the course BIOLOGY 101 taught by Professor Martin during the Fall '08 term at Rutgers.

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Prenatal testing for genetic disease - Prenatal testing for...

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