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cell bio exam 1 answers - BIO 320 Dr Bushart Midterm Exam#1...

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BIO 320 Dr. Bushart Print Name:___________________________ Midterm Exam #1 11 AM Monday February 9, 2009 General instructions : Read each question carefully and don’t hesitate to ask if a question seems unclear. Trying to provide an answer for every question is advantageous; you will not be penalized for guesses. The short-answer questions have specific answers, although for some, more than one answer is possible. If possible, answer each question in the space provided, but if needed, continue on the back. If you use a diagram as part of your answer, be sure to also include appropriate labeling and/or a short written explanation. To receive full credit you must clearly and fully answer the question being asked. Partial credit may be given in 0.5 point increments. This exam is worth 100 points (the points for each section/question are noted in parentheses). Short answer (100 points): There are 7 short-answer questions over 3 pages. Write a clear concise answer for each question. Some questions may have more than one possible answer but require you to defend your choice. Be sure you include clear explanations. Make sure your response answers the question being asked! 1. (11 points) Mutations that lead to changes in the amino acid sequence (primary structure) of proteins have the potential to impact their function, but do not always do so. Imagine a protein in which a serine residue (which has a hydroxyl or “–OH” functional group) is important for the tertiary structure of a protein because it hydrogen bonds with another amino acid. If a mutation altered the amino acid the serine bonds with , which class(es) of amino acids should have the greatest disruption to this protein’s function? Why?
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