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EEMB 3 Lecture - EEMB 3 Lecture History of Life on Earth...

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EEMB 3 Lecture History of Life on Earth Spontaneous Generation Francisco Redi – Meat / flies -Life does not arise from inanimate matter, life originates from life Louis Pasteur – Two jars, boil, stems, w/ dust = growth -Microorganisms come from other microorganisms only Theories to explain Origin of Life Panspermia (ET) -ALH 84001, AA, Comets/water -ET input hypothesis, via asteroid/comet collisions w/ earth Chemical Evolution -Simple molecules + water = large molecules 1. Accum. Small org molec, little O2 (reducing atmosphere), UV can penetrate -Spontaneous synthesis of AA, Nucleotides aided by UV radiation and Lightning 2. Polymerization to form macromolecules Divalent cation catalysts, abiotically reproduce 3. Polymers enclosed in membrane A) Protobionts – aggregate of abiotically produced organic molec which have metabolism and excitability (Oparin 1924) Living cells evolved from coacervates (mix of protein and polysaccharides that self assemble bc hydrophobic) B) Liposomes – forms spont w/ lipid and water Boundary, internal polymers, enzymatic funx, simple cell rep 4. Evolution of cell properties Need catalyst, information, energy source DNA mRNA Protein (catalyst) Catalystic RNA – ribozymes (simple RNA molecule) info/catalyst Evolution as DNA RNA template for DNA, RNA catalyst DNA storage, DNA more stable, then evolve more Protein Catalyst -Past earths phys/chem. Conditions Life arose several times? Earth – 4.5 BYA Oceans - 4.2 BYA Rock – 4 BYA Microfossils - 3.5 BYA
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Lecture 10/3/08 History of Microbiology -1650 Microscopes to see bacteria -1850 Bacteria responsible for degradation and fermentation (Pasteur) Antiseptic surgery (Lister) -1850 – 1910 Culture techniques, pathogens identified (Koch, Beijerinik) -1980 Culture independent techniques (Pace) molec techniques (Woese) 3 Main branches of Microbiology 1. Medical MicBio and Immunology (Koch) 2. Industrial Microbiology (Pasteur) a. Pharmaceutical, Vitamin, AA, Alcohol, industrial chemicals 3. Environmental Microbiology Char. Prokaryotes
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