15Chemostat2-update - Course Modifications/Clarifications...

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Unformatted text preview: Course Modifications/Clarifications More Homework (more exam prep) Will drop your one lowest score homework and average the rest. Average grade will be ~3.4 (between B+ and A-) Exam is designed to have some questions you may not have previously seen Office hours are immediately after class (whenever possible) and by email appt More group problems and explanations in class Single Cell Type; Continuous Culture S ubstrate + Cells P roduct + More Cells X : cell mass S ubstrate P roduct E nzyme N : cell number Batch Growth 0.10 1.00 10.00 100.00 5 10 15 20 25 What if you want to keep growth rate like this? Product formation may be better, mechanisms. Chemostats D g = Page 192 F: flow rate D D K S S K S D m S s m g = + = = Should be X max determined from vs S; Not X vs t! Chemostat Culture Weve kind of ignored maintenance energy How can we account for that? d g k D + = Chemostat Accounting for Maintenance Energy Substitute into : dt dS V Y X q V Y X V FS FS R S P p R M S X g R o = / / 1 1 Materials balance (Substrate): D = F/V R : Negligible product formation @ steady state: d...
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This note was uploaded on 03/03/2009 for the course BIOMEDE 321 taught by Professor Takayama during the Winter '08 term at University of Michigan.

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15Chemostat2-update - Course Modifications/Clarifications...

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