IB 117 _1 Perph NS Analgesics

IB 117 _1 Perph NS Analgesics - IB 117 Thomas Carlson...

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IB 117  Thomas Carlson Peripheral nervous  system analgesics &  anti-inflammatories  Plant origin  Geographical /cultural  origins Mechanism of action cocaine and  derivatives procaine,  tetracaine, & lidocaine Erythroxylum  coca South  American  Andes Mtns Local blockade of nerve  impulses acetylsalicylic acid,  salicylic acid,  Filipendula  ulmaria Europe Inhibits cyclooxygenase which  inhibits prostaglandin synthesis salicin, saligenin Salix alba Europe
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Unformatted text preview: Inhibits cyclooxygenase which inhibits prostaglandin synthesis diosgenin as precursor to glucocorticoids Dioscorea mexicana Mexico Blocks cytokine production. Inhibits phospholipids conversion to arachidonic acid which inhibits prostaglandin synthesis capsaicin Capsicum annuum & Capsicum frutescens Tropical America Agonist at capsaicin receptor, a heat-activated ion channel pain pathway...
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  • Summer '08
  • prostaglandin synthesis, Inhibits phospholipids  conversion, South  American  Andes Mtns Europe Europe, prostaglandin  synthesis Agonist

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