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Practice Problem for MT2 (for student)

# Practice Problem for MT2 (for student) - Practice Problem...

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Practice Problem for MT2 1. In dogs, the genetic control of blindness is unknown. A pedigree is shown below. Blind individuals have been shaded black. Assume that dogs Ib and IIe are heterozygous for the blindness gene. (i) Is this pedigree consistent with a X-linked recessive trait? (ii) Is this pedigree consistent with a X-linked dominant trait? (iii) Is this pedigree consistent with an autosomal recessive trait? (iv) Is this pedigree consistent with an autosomal dominant trait? (v) Propose a cross using any of the dogs in the pedigree that would allow the true inheritance pattern to be determined. Give the expected results and the conclusions that would be drawn in each case. 2. A family has a rare disorder, as indicated by the red symbols in the family tree: a) What is the mode of inheritance of this disorder? b) Cite 2 facts about the pedigree that justify your conclusion. c) What is the probability that the individual IV-1 is a carrier? Explain how you determined the probability. 3 . You are studying three autosomal recessive mutations in Drosophila that are linked: rosy, hairy, and wobbly. You cross a fly from a pure-breeding wobbly strain to a fly from a pure-breeding hairy, rosy strain to obtain an F1. You then cross the F1 flies to flies from a pure-breeding rosy, hairy, wobbly strain to obtain the following F2: 12 rosy wobbly 84 hairy rosy wobbly 407 hairy wobbly 1941 wobbly 2031 hairy rosy 12 hairy 408 rosy 105 wild type TOTAL 5000 Derive the most accurate map you can of the order of these genes and the distances between them. State the amount of interference, if any. SHOW ALL YOUR WORK. I II III a b a b c d e c d a b

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4. In tomatoes, tall (D) is dominant over dwarf (d) and smooth fruit (P) is dominant over pubescent fruit (p), which is covered with fine hairs. A farmer has two tall and smooth tomato plants, which we will call plant A and plant B. The farmer crosses plants A & B with same dwarf & pubescent plant and obtains the following numbers of progeny: Progeny of Plant A Progeny of Plant B DdPp 122 2 Ddpp 6 82 ddPp 4 82 Ddpp 124 4 a) what genotype of plant A and plant B?
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Practice Problem for MT2 (for student) - Practice Problem...

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