Blood_Age_Reversal - It's all in the blood Can it really...

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It's all in the blood: Can it really reverse ageing? Introduction: Terms or phrases like "fountain of youth" seems appropriate only in the realms of fiction and fairytale but recent scientific evidences are pointing towards a completely different
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story altogether. Researchers are really excited about a certain protein factor found abundantly in the blood of young individuals that can supposedly reverse or at least slow down the ageing process. Studies have shown that the anti-ageing effect of this protein factor is remarkably visible in the heart tissue, brain and even in the muscles. According to a scientist named Amy Wagers who works with stem cells at Harvard University, this protein factor is produced naturally in the blood and its concentration declines with age (Kaiser, 2014). The factor has noticeable anti-effect in multiple tissues and these observations were further corroborated by another group of researchers who observed that the learning capabilities of old mice improved significantly when injected with plasma taken from young mice (Kaiser, 2014). Hype or reality: Age reversal has already generated lot of interest since ages and it is a challenge to determine if things are more hyped up or real. None the less, discovery of the anti- ageing blood reversal factor is a nice starting point and only further studies will tell if the effects are real and substantial. A recent study carried out by Loffredo et al. (2013) reported the isolation of a protein called the growth differentiation factor 11 from the blood of young mice that can potentially arrest age-induced myocardial thickening in old mice. Another recent study was able to demonstrate that the growth differentiation factor 11 can significantly rejuvenate skeletal muscles in old mice. The researchers through the process of parabiosis supplied a recombinant form of the protein to old muscles tissues and observed that the process dramatically improved muscle strength and endurance capabilities (Sinha et al., 2014). Improved healthcare facilities in the 21st century has significantly increased the lifespan of people but the major trade-off of
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this progress are the age-induced physical and cognitive defects that are putting lot of pressure on the existing healthcare resources. Researchers are under pressure to find ways that can help reduce the effects of ageing and discovery of entities such as growth differentiation factor 11 is generating lot of interest and hope in this regard (Hebert, Scherr, Bienias, Bennett & Evans, 2003); (Bishop, Lu & Yankner, 2010). Another study carried out by Villeda et al. (2014) reported that old mice that received young blood
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