Lecture2-2009W - Basis of Intercellular Communication...

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Basis of Intercellular Communication Common properties (1) Aquatic environment - water, ions (2) Biomembranes (3) Signal transduction (4) Demand for energy Water - the unique solvent c polar molecule c hydrogen bond b form networks between positively charged H atom and negatively charged oxygen atom Oxygen Hydrogen b hydration
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Hydration c Ionic compounds (=electrolytes) ex) Sodium chloride c Non-polar molecules c Amphipathic compounds b hydrophilic polar head + hydrophobic non-polar tail ex) Sodium oleate Properties of Solutions (= solutes + solvents) c Solubility – hydrophilic vs. hydrophobic c Concentration of solutions - mole: 6.02x10 23 atoms, ions, or molecules of a substance - molecular weight: glucose -180 Dalton, NaCl - 58.5 - molarity (mol/L, M) b cf) Molality (mol/Kg) - equivalent (eq): [M] x # of charges the ion carries c pH: acids (=HA) & bases (=A - ) - biologically important ionic solutes - H + & OH - - acid: a molecule that donates H + to a solution - base: a molecule that decreases [H
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Lecture2-2009W - Basis of Intercellular Communication...

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