Lecture2-2009W - Basis of Intercellular Communication...

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Basis of Intercellular Communication Common properties (1) Aquatic environment - water, ions (2) Biomembranes (3) Signal transduction (4) Demand for energy Water - the unique solvent checkbld polar molecule checkbld hydrogen bond barb2right form networks between positively charged H atom and negatively charged oxygen atom Oxygen Hydrogen barb2right hydration
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Hydration checkbld Ionic compounds (=electrolytes) ex) Sodium chloride checkbld Non-polar molecules checkbld Amphipathic compounds barb2right hydrophilic polar head + hydrophobic non-polar tail ex) Sodium oleate Properties of Solutions (= solutes + solvents) checkbld Solubility – hydrophilic vs. hydrophobic checkbld Concentration of solutions - mole: 6.02x10 23 atoms, ions, or molecules of a substance - molecular weight: glucose -180 Dalton, NaCl - 58.5 - molarity (mol/L, M) barb2right cf) Molality (mol/Kg) - equivalent (eq): [M] x # of charges the ion carries checkbld pH: acids (=HA) & bases (=A - ) - biologically important ionic solutes - H + & OH - - acid: a molecule that donates H + to a solution
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  • Spring '09
  • Tanda
  • Atom, Ion, hydrophobic non-polar tail, polar molecule hydrogen

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