Lecture9-2009W - Passive transport(B Facilitated passive transport Protein pores channels ionophores Carrier-mediated uniporters coupled

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Passive transport: (B) Facilitated passive transport c Protein pores / channels - ionophores c Carrier-mediated - uniporters - coupled transporters (i) symporters (ii) antiporters Active transport: up-hill transport Basic properties: (1) carrier-mediated (2) metabolism energy required b sensitive to respiratory poisons & oxygen deficiency (3) create a voltage difference b electroneutral vs. electrogenic (4) examples b Na + -K + ATPase (pump), the best-known b Ca 2+ ATPasein the SR of muscle b H + -K + ATPase in stomach b H + ATPase in gills and kidneys
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b transporter = ATPase b e.g. Na + -K + ATPase 2. Secondary active transport: b immediate energy source = electrochemical gradient (not ATP) b cotransporters vs. countertransporters Ionic gradient as a source of Energy b Energy release occurs when the ions are allowed to flow down their gradient across the membrane 1. Production of electrical signals e.g. Na + flux thru the channels 2. Chemiosmotic energy transduction e.g. ATP production in Mt. 3. Uphill transport of certain molecules
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This note was uploaded on 03/11/2009 for the course BIOS 342 taught by Professor Tanda during the Spring '09 term at Ohio University- Athens.

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Lecture9-2009W - Passive transport(B Facilitated passive transport Protein pores channels ionophores Carrier-mediated uniporters coupled

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