Lecture25-2009W - h myosin-linked regulation Ca 2...

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skeletal vs. cardiac Cardiac muscle Cardiac muscle: excitation-contraction coupling
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Smooth muscle A. Single-Unit SM barb2right gap junction barb2right myogenic barb2right e.g. intestinal tract B. Multi-Unit SM barb2right No gap junction barb2right neurogenic barb2right e.g. iris muscle of the eye Contraction of smooth muscle head2right Ca 2+ from SR or through V-G Ca 2+ Ch. head2right Ca 2+ pumps in the plasma memb. & SR
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Unformatted text preview: h myosin-linked regulation Ca 2+ calmodulin + Myosin LC kinase Myosin LC Myosin LC-P phosphatase Unusual features of SM contract. Latch state- vertebrates- ATP binding very slow- termination: myosin LC phospho. Catch state- invertebrates- Mollusk catch muscle (adductor muscle of bivalves)...
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