Lecture25-2009W

Lecture25-2009W - h myosin-linked regulation Ca 2+...

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skeletal vs. cardiac Cardiac muscle Cardiac muscle: excitation-contraction coupling
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Smooth muscle A. Single-Unit SM b gap junction b myogenic b e.g. intestinal tract B. Multi-Unit SM b No gap junction b neurogenic b e.g. iris muscle of the eye Contraction of smooth muscle h Ca 2+ from SR or through V-G Ca 2+ Ch. h Ca 2+ h No troponion
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Unformatted text preview: h myosin-linked regulation Ca 2+ calmodulin + Myosin LC kinase Myosin LC Myosin LC-P phosphatase Unusual features of SM contract. Latch state- vertebrates- ATP binding very slow- termination: myosin LC phospho. Catch state- invertebrates- Mollusk catch muscle (adductor muscle of bivalves)...
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Lecture25-2009W - h myosin-linked regulation Ca 2+...

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