{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

8B-handout-feb4

8B-handout-feb4 - Chem 8B Handout for Feb 4 2009 Organic...

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Chem 8B, Handout for Feb 4, 2009 Organic Oxidation and Reduction reactions (pp 269-270, 329), and Imines (pp 331-332) Oxidation = add oxygen by converting C-H bond into a C-O bond (increase # of C-O bonds) Reduction = add hydrogen by converting C-O bond into a C-H bond (reduce # of C-O bonds) Reducing agents add H 2 , or a hydride (H: ) to increase the number of C-H bonds. Examples of chemical reducing agents used with carbonyls are NaBH 4 and LiAlH 4 . (see page 329). There are also enzymes that can add H 2 to reduce a carbonyl. Examples of chemical oxidizing agents include O 2 , chromium reagents (such as CrO 3 , H 2 CrO 4 , and Na 2 Cr 2 O 7 ), and AgNO 3 . Notice a trend? They all have lots of oxygen atoms in the reagents. In addition to chemical reagents, enzymes can also perform oxidation reactions. Metabolic oxidation reactions are some of the most important reactions that occur in biological systems. We have already examples of biological oxidations with the enzyme cytochrome p450 (pages 280-281), but there are other enzymes that can also oxidize compounds. For example, alcohol dehydrogenase is an important enzyme that can
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}