8B-prozac-jan7 - Chem 8B winter 2009 Case study with Prozac...

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Chem 8B, winter 2009 Case study with Prozac : 1) If you have a sample of potentially-contaminated water, how do you detect if any organic molecules are in the water? 2) Once you detect that there may be organic contaminants, how do you know if Prozac or another pharmaceutical drug is one of the contaminants? 3) How can we “purify” (ie, separate) out the organic contaminants? 4) If you perform an LC analysis and identify that there are two different molecules present in the water (a chromatogram with two peaks, see below) and you think one of them is Prozac and one of them is epicatechin. Which peak corresponds to which molecule? O HO OH OH OH OH epicatechin (a naturally-occuring antioxidant flavonoid found in chocolate and green tea)
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Unformatted text preview: Other Sample Questions: 1) There is a popular experiment using chromatography to analyze the food-coloring dyes in M&M candies. How would you identify if a red skittles and a red M&M use the same red dye molecule? 2) Predict the order that the following three compounds will separate and elute from (i.e. come off) a column using gas chromatography . Fill in the boxes (below the molecules) with your prediction, where 1 = the first compound to elute, and 3 = the last compound to elute from the column. The predicted chromatogram is shown below. peak 1 peak 2 peak 3 time GC chromatogram peak detection OH H 3 C O CH 3 CH 3 H 3 C time LC chromatogram N H O Me CF 3...
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