lecture_notes_11_21_07

lecture_notes_11_21_07 - Johanne Brunet Biocore 301, fall...

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1 Johanne Brunet Biocore 301, fall 2007, Population Genetics LECTURE summary for November 21, 2007 Lecture 5: Learning objectives - Impact of mutation on gene and genotype frequencies - Migration and gene flow and impact on gene and genotype frequencies - Genetic drift and impact on gene and genotype frequencies - Taxonomic and biological species concepts - Allopatric and sympatric speciation MUTATION - Ultimate source of genetic variation - Raw material for evolution - Created by changes in the genetic material (point mutation; gene duplication etc…) - Most mutations are deleterious (will be selected against) as opposed to advantageous. - Many mutations have no phenotypic effect (neutral mutations) and thus are not affected by selection. - Mutation rate u - Forward mutation - Spontaneous forward mutations rates are typically rather small 10 -4 to 10 -6 mutations per allele per generation - Thus the tendency for allele frequencies to change as a result of recurrent forward mutation is very small over the course of a few generations; - Mutations ALONE have small effects on gene frequencies except over very long
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This note was uploaded on 04/29/2008 for the course BIOCORE 301 taught by Professor Howell during the Fall '07 term at Wisconsin.

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lecture_notes_11_21_07 - Johanne Brunet Biocore 301, fall...

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