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Unformatted text preview: Carolyn Johnson Intro to Biology Research Response to 2b. The evidence presented in the paper “Viable offspring derived from fetal and adult mammalian cells” posted to Nature in 1997 does not completely justify the claim that the only remaining lamb born, Dolly, is the first mammalian clone developed from adult tissue. The scientists involved in Dolly’s creation do not present enough conclusive proof and data that Dolly came exclusively from the adult mammary or adult stem cells of the pregnant donor ewe. Dolly was the only pregnancy and live lamb resulting from thirteen recipients of embryos created from cells of the mammary gland of a pregnant six year old Finn Dorset ewe. There has been significant debate over what type of cells were actually cultured from the mammary gland, given that the primary culture contained approximately 90% mammary epithelial, but the remaining 10% could have been undifferentiated adult stem cells or fetal stem cells, given that the donor ewe was pregnant at the time of...
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This note was uploaded on 03/15/2009 for the course BIOL 211 taught by Professor Ta during the Spring '09 term at UNC.
- Spring '09