DollyGroupC - Were Not Convinced Other evidence that we'd...

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We’re Not Convinced.  We’re Not Convinced.  Clint Fuller, Carolyn Johnson,  Chau Nguyen, Matthew Saponaro Other evidence that we'd like to see before concluding that nuclei from adult cells can support normal development of clones.
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Other Things We’d Like to  Other Things We’d Like to  Know Know Why such a high loss of fetuses?  13 recipients and one pregnancy from the  mammary gland Of 6 live births, only one survived – Dolly Autopsies were “inconclusive” – only 2 deaths  explained. 
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Need for Control Groups Need for Control Groups Can’t tell if survivability rates are  normal Low percentage of fetal survivability What are the norms for other invitro  pregnancies of lambs?
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Dolly’s Origin Dolly’s Origin What kind of cells did Dolly 
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Unformatted text preview: actually originate from? ◦ Sample was 90% mammary gland cells Possibility of fetal cells or adult stem cells in the sample. Article Related Issues Article Related Issues Errors in the article make it difficult to understand. (Figure 1) Would like to be able to understand the microsatellite image better. Some elements unclear – how the weight and gestation periods are in the range for the donor and not the recipient breed. Follow-Up Questions on the Follow-Up Questions on the Study Study Monitor Dolly’s survivability – is she an anomaly? ◦ We would like to see if she has a normal development rate (in comparison to her breed) Microsatellite analysis of the recipient ewes...
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  • Spring '08
  • Mbadugua
  • Cell nucleus, Mammary Gland, stem  cells, Microsatellite, mammary gland  cells, adult stem  cells

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