Fat Virus Alternate Claim

Fat Virus Alternate Claim - Proof that the other stem cells...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
Click to edit Master subtitle style 10/5/09 Fat Virus Alternate Claim Carolyn Johnson
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
10/5/09 Alternate Hypothesis Adenovirus-36 attacks receptors present on the  surface of human adipose-derived stem/stromal  cells, signaling for it to become an adipose cell or  accumulate more lipids. These receptors must be  present for the cell to be converted or influenced-  other stem cell types won’t be affected the same  way.  Experiment to prove/disprove: Introduce Ad-36 to  other cell type derived stem cells, discover if it 
Background image of page 2
10/5/09 Results – Claim proven Percentage of particular derived stem cell sample that  became an adipose cell and accumulated lipids. The more  specific the cell type, the less receptors available for the 
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
10/5/09 Claim Proven – Follow Up Data
Background image of page 4
Background image of page 5
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Proof that the other stem cells don’t express the receptors: One possible way to show this would be to fluorescently tag the virus, and using fluorescent microscopy, measure the intensity of attack on each cell type. The other stem cells (and the specialized WBC) should show little to no fluorecence. This experiment is important in order to show that the connection between the receptors and the virus is indeed valid. 10/5/09 Results – Claim Disproven All derived cell types show the same percentage of sample conversion, indicating that the virus shows no specificity towards cell signalling receptors in its attack. No clear preference is given to one cell type or another....
View Full Document

Page1 / 5

Fat Virus Alternate Claim - Proof that the other stem cells...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online