Lecture 15 Chapter 13_2

Lecture 15 Chapter 13_2 - Introduction to Genetic Analysis...

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Unformatted text preview: Introduction to Genetic Analysis Ninth Edition Anthony J. F. Griffiths, Susan R. Wessler, Richard C. Lewontin, and Sean B. Carroll CHAPTER 13 Genomes and Genomics Lecture 2 Copyright 2008 W H Freeman and Company Human Genome: Important Numbers 1. 23 chromosomes in haploid genome. 1. ~3 billion (3 x 10 9 ) base pairs of DNA in haploid genome. 1. ~25,000-30,000 different genes in haploid genome. 1. ~1-4 splice forms per gene = ~100,000 transcripts 1. Average-sized protein has ~300 amino acids About 50% of the Human Genome is Comprised of Transposable Elements LINEs : L ong in terspersed e lements SINEs : S hort in terspersed e lements What else maybe there in our genome? Only 1-2% is protein coding sequence. 4.5% is conserved and under selection. Cis-acting elements do not account for this 2.5% extra conservation....
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Lecture 15 Chapter 13_2 - Introduction to Genetic Analysis...

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