lecture5 - Ventilation Review AcuteExercise Response...

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Ventilation Review Acute Exercise Response Regulation Training Adaptations
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Exercise (submax)
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TABLE 12-1
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V A = (V T - DS)F (500 ml - 150 ml) x 1 = 350 ml = V A V A = alveolar ventilation V T = tidal volume DS = physiological dead space F = breath frequency
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TABLE 12-2
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Submax Steady-State Exercise
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Neural Inputs Central Command Motor Cortex (feed-forward mechanism) Peripheral Neural Inputs Muscle receptors (afferent) Mechanoreceptors muscle spindles, Golgi tendon bodies, joint receptors (afferent)
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Humoral Factors (blood borne) Central Chemoreceptors located on surface of medulla of Respiratory Center in brain – Receptors sensitive to changes in PCO 2 in cerebral spinal fluid (via H + ) – During exercise, CO 2 production stimulates these receptors blow-off more CO 2 to maintain arterial levels
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Humoral Factors (con’t) Peripheral Chemoreceptors located in carotid & aortic bodies – Receptors sensitive to changes in PaO 2 , PaCO 2 , and pH – During exercise a PaO
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lecture5 - Ventilation Review AcuteExercise Response...

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