lecture 7 - ↑ Local Blood Flow ↑ Mito O 2 use → ↓...

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Heart & Systemic Circulation Acute Exercise Fick Equation Cardiac Output Blood Flow – (a-v)O 2 difference Training Adaptations
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VO 2 = Q x (a-v)O 2 Diff HR x SV Local Blood Flow Mito O 2 use PO 2 cell Shift in O 2 -Hb Dissociation curve Fick Equation
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Cardiac Output Cardiac Output (Q) = HR x Stroke Volume
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Heart Rate Response to Exercise Regulation
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Regulation of Heart Rate Intrinsic Extrinsic
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Intrinsic SA Node AV Node Purkinje Fibers Atria Stretch Reflex
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Extrinsic Sympathetic & Parasympathetic Nervous System Circulating Catecholamines
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TABLE 15-1
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Stroke Volume Response to Exercise Regulation
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Regulation of Stroke Volume Intrinsic Extrinsic
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Intrinsic Stretching of Myocardium (preload) Frank-Starling Curve
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Unformatted text preview: ↑ Local Blood Flow ↑ Mito O 2 use → ↓ PO 2 cell Shift in O 2-Hb Dissociation curve Ways to increase blood flow to active muscle • ↑ Cardiac Output • ↑ Vasodilation of bloods vessels in active muscles • ↑ Vasoconstriction of blood vessels in less essential tissues (Shunting) TABLE 15-1 ↑ ↑ * * * * Local autoregulation of blood flow during exercise • ↓ [PO 2 ] • ↑ [PCO 2 ] • ↑ [H + ] TABLE 15-2 5.2 L/min 21.0 L/min VO 2 = Q x (a-v)O 2 Diff ↑ HR x ↑ SV ↑ Local Blood Flow ↑ Mito O 2 use → ↓ PO 2 cell Shift in O 2-Hb Dissociation curve O 2 Uptake & Utilization • O 2-Hb dissociation curve • Cell PO 2 • Mitochondria 2 exercise ↓ can to 15-20 mm Hg Training Adaptations TABLE 16-2 TABLE 14-1 (a-v)O 2 difference • ↑ Capillary/Fiber ratio • ↑ Red blood cell number • ↑ Mitochondria number...
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