MH3 - Minh Le, m8le@ucsd.edu; BIPN 100 OH: 11-11:50a...

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m8le@ucsd.edu ; BIPN 100 OH: 11-11:50a Mondays, Café Roma Handout 3 Summation: - Temporal G.P. close enough together in time so APs could add up and pass threshold - Spatial G.P. from pre-synaptic cell, but not sufficient for depolarization. But if different synapses fire at same time, their G.P.s may add up and have an above- threshold stimulus. - Remember, these graded potentials may be inhibitory signals too (IPSP) may decrease chance of an AP Ex) GABA binds to GABA A Receptor Increase Cl- flow in (barbiturates) Post-Synaptic Inhibition vs. Pre-Synaptic Inhibition - Post-Synaptic Inhibition is IPSP at dendrites to cell body - Pre-Synaptic Inhibition synapse at axon terminal that provides IPSP synaptic transmission inhibited. Covergence vs. Divergence - Covergence multiple synapses from pre-synaptic neurons to one post-synaptic neuron - Divergence pre-synaptic neuron synapses to multiple post-synaptic neurons the signal amplifies. Spinal Chord: begins at base of the brainstem and runs down the spinal column. - Spinal nerves: cervical, thoracic, lumbar, sacral a. Composed of two nerve (figs 9-4, 7,8) b. Dorsal Root: sensory (afferent) neurons enter spinal chord ascending tracts c. Ventral Root: motor (efferent) neurons enter spinal chord descending tracts Motor Units: motor neuron that innervates different muscle fibers - can have motor unit innervate a lot of muscle fibers or have a fine-tuned motor neuron innervating individual muscle fibers - The same applies to sensory units - More sensitive with two point discrimination
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MH3 - Minh Le, m8le@ucsd.edu; BIPN 100 OH: 11-11:50a...

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