Apr.17notesanatomy - Electrolyte balance -Electrolyte...

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Electrolyte balance -Electrolyte balance affects water balance. -Conc. Of some electrolytes very important for cell functions, particulary sodium and potassium Most common problems involve sodium Less common but more serious problems involve potassium Sodium -it’s important for neuron and muscle cell function -sodium also most important electrolyte for water movement (osmosis) -total sodium determined by: Uptake from diet rate of absorption varies directly with amount in diet Excretion by kidney (and to lesser extent in sweat) Regulation -Aldosterone “salt-retaining” hormone, causes insertion of Na/K pumps in DCT and CD which increases reabsorption Only effector that acts directly on sodium content -ADH indirectly affects concentration by affecting water volume -Atrial Natriuretic Peptide (ANP) inhibits sodium and water reabsorption at DCT and CD by inhibiting Na/K pumps. -Imbalances Rare b/c water will always move around to balance out sodium conc. Hypernatremia high blood sodium conc. o Can result from dehydration, diuretic use, hypersecretion of aldosterone o Symptoms reflect water deficiency as much as sodium excess Hyponatremia low blood sodium conc. o
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This note was uploaded on 03/22/2009 for the course BIOL 252 taught by Professor Johnson during the Spring '07 term at UNC.

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Apr.17notesanatomy - Electrolyte balance -Electrolyte...

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