The Endocrine System

The Endocrine System - The Endocrine System Intercellular...

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The Endocrine System Intercellular Communication Direct Communication-through gap junctions. Chemical mediators-ions, small solutes, lipid-soluble materials Paracrine communication -through extracellular fluid Endocrine communication -through the circulatory system. Uses hormones. Synaptic communication -across synaptic clefts. Use neurotransmitters. What are hormones and what do they do? -Chemical messengers that travel via bloodstream -Bind to receptors either on surface or inside target cells -Have widely varying effects on targets. Receptors on cell membrane of target cells activate second messengers inside target cell. Receptors inside target cells can directly affect genetic machinery. *All for 16.2 Overview of the Endocrine Organs -Hypothalamus-production of ADH, oxytocin, and regulatory hormones Command central of the endocrine system-hypothalamus and pituitary gland Recognize hypothalamus 3 nuclei-supraoptic, paraventricular, arcuate and periventricular (lateral lateral) Infundibulum Capillary bed-hypophyseal system. Pituitary gland-anterior and posterior lobes. Supraoptic and Paraventricular Nuclei Neurons make hormones Release into bloodstream at capillary bed of Posterior pituitary-no endocrine cells of its own. Hormones Involved o Antidiuret Hormone (ADH) -Also called vasopressin -Made in both hypothalamic nuclei -Causes increased water uptake by kidneys Oxytocin (OT) Made in both hypothalamic nuclei
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In females contraction of uterus during labor and milk ejection during suckling In males contraction of ductus deferens (sperm duct) and prostate gland during ejaculation.
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This note was uploaded on 03/22/2009 for the course BIOL 252 taught by Professor Johnson during the Spring '07 term at UNC.

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The Endocrine System - The Endocrine System Intercellular...

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