Chronic stress decreases immune function does

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: learning suppression • Rats showed CR of immune suppression to CS of Rats saccharin solution after pairing with an immune suppressing drug (US) suppressing – Nervous and endocrine systems Nervous communicate via cytokines, messengers secreted in the immune system secreted Lecture 22 37 Psychoneuroimmunology Stress • Acute stress manipulation studies • Naturalistic study of chronic stress • Often studied by looking at markers of immune function in blood • Wound healing studies • Sympathetic nervous system activation influences immune function Immune System • Imperfect relationship; requires exposure • Mostly studied in animals to date; • Some studies look at development of cold symptoms following exposure to virus as a function of stress Lecture 22 Disease 38 PNI Findings • Medical students show lower numbers of Medical NK, T, and % of total lymphocytes around exams than at other times exams • Wound healing slower during exams than Wound on vacation on • Marital conflict linked to poorer response Marital to immunization and slower wound healing to Lecture 22 39 PNI Findings • Caregivers have slower healing, worse Caregivers immune functioning, higher mortality immune • Bottom line: Stress, esp. chronic stress, Bottom decreases immune function decreases • Does reducing stress help? A little Does (hypnosis, relaxation, CBT) (hypnosis, Lecture 22 40 PNI Mechanisms • CNS and immune system communicate via CNS peripheral NS connected to thymus, spleen, lymph nodes lymph • CNS communicates via hormones (e.g., CNS releasing factors) releasing • Autonomic NS influences immunity by controlling Autonomic release of epinephrine, norepinephrine, cortisol release • Imm...
View Full Document

This note was uploaded on 03/22/2009 for the course PSYCHOLOGY 830 taught by Professor 346 during the Spring '09 term at Rutgers.

Ask a homework question - tutors are online