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Rejection immune system attacks transplanted organ

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Unformatted text preview: -cell growth – Helper T-cells (CD4) stimulate lymphocytes to reproduce and attack – Suppressor T cells slow down immunity process Lecture 22 30 Specific Immune System Response: Humoral (Antibody-Mediated) Immunity • Attacks pathogens while they are still in the body fluids, before they invade cells • B cells (which mature in bone marrow) • Antibodies (immunoglobulins, Ig) are proteins that attach to invaders. 5 types – IgG, IgM, IgA, IgD, IgE Lecture 22 31 Lecture 22 32 Primary vs. Secondary Immune Responses • Memory Lymphocytes: – T-cells and B-cells, sensitized to specific antigen – Replicate, held in reserve – More rapid (secondary) response to re-exposure • Way vaccines work Lecture 22 33 Lecture 22 34 Immune System Disorders • Immune deficiency – AIDS-- HIV destroys T-cells and macrophages • Allergies-- extreme immune reaction to allergens • Autoimmune diseases -- immune system attacks the body (suppressor T cell dysfunction) – Lupus – Rheumatoid arthritis Lecture 22 35 Immune System Disorders • Transplant rejection – Immune system attacks transplanted organ – Counteracted by immunosuppressing drugs – Leaves body vulnerable to other pathogens • Cancer? According to immune surveillance theory Lecture 22 36 Psychoneuroimmunology • Study of relations among behavior and the Study nervous, endocrine, and immune systems nervous, – Proposed after Ader & Cohen found immune Proposed suppression influenced by...
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