Outline 22-Evolution in Medicine

Outline 22-Evolution in Medicine - BSCI 106 Dr Sara Via...

Info icon This preview shows pages 1–3. Sign up to view the full content.

BSCI 106 Outline 22 Fall 2008 p. 1 Dr. Sara Via Evolution in Medicine -Disease occurs in populations, which evolve! -- Body is a population of cells -- Sick individuals harbor populations of bacteria, viruses, etc -- Populations of disease organisms can live outside the body -- Behavior in human populations affects disease transmission Cancer-- Natural selection among cells - Sometimes control of cell cycle goes awry - Cells that don’t stop dividing form tumors rob other cells of resources - Can break away from original location and spread around the body - Cancer cells have increased survival and reproduction! - Characteristics of normal cells * Reproduce themselves exactly * Stop reproducing at the right time * Stick together in the right place * Self destruct if they are damaged * Become specialized or 'mature' Cancer-- How do cells become cancerous renegades? - Normal Cells * growth genes normally turned off * tumor suppressor genes normally turned on - Mutations can affect regulation of these genes and others involved in cell division - Characteristics of cancer cells * They carry on reproducing * They don't obey signals from other neighboring cells * They don't stick together * They don't become specialized, but stay immature * They don't die if they move to another part of the body Evolution of HIV HIV the virus that causes AIDS It is a RETROVIRUS-- copies its DNA into the host’s DNA
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

BSCI 106 Outline 22 Fall 2008 p. 2 Dr. Sara Via Reverse transcription very error-prone, no repair VERY high mutation rate among 10 10 virus
Image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern