08 -- Visual system part 2

08 -- Visual system part 2 - Retinal Processing Bipolar...

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Retinal Processing
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Bipolar Cell Connectivity Bipolar cells Receive input from group of photoreceptors RECEPTIVE FIELD RECEPTIVE FIELD Direct input   field  center center Indirect   field  surround surround ; input from from PR’s  by way of horizontal cells Receptive field
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Direct Interaction Between PR’s and Bipolar Cells Dark PR depolarized PR glutamate release high ON bipolar cell hyperpolarizes Bipolar cell not active  when center of  receptive field not illuminated Light PR hyperpolarizes PR glutamate release low ON bipolar cell depolarizes Bipolar cell active  when center of  receptive field illuminated There happens to be 2 different types  of Bipolar cells, characterized by their response to  stimulation from the PR’s in the  CENTER  of their receptive field FIRST ONE WE WILL DISCUSS =  “ON” or “ON-Center” “ON” or “ON-Center”  Bipolar cells Glutamate is the neurotransmitter  released by PR released by PR “ON” bipolar cells have  ON” bipolar cells have  mGluR6 mGluR6  receptors receptors that cause   that cause  HYPERPOLARIZATION HYPERPOLARIZATION
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Dark PR depolarized PR glutamate release high OFF bipolar cell depolarizes Bipolar cell active  when center of  receptive field NOT illuminated Light PR hyperpolarizes PR glutamate release low OFF bipolar cell hyperpolarizes Bipolar cell not active  when center of  receptive field illuminated THE OTHER ONE =  “OFF” or “OFF-Center”
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This note was uploaded on 03/23/2009 for the course BIOL 450 taught by Professor Jeremyingraham during the Spring '09 term at UNC.

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08 -- Visual system part 2 - Retinal Processing Bipolar...

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