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07 -- 402_S2009_Reproductive Behaviors exercise ANSWERS

07 -- 402_S2009_Reproductive Behaviors exercise ANSWERS - 1...

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1. What are the CLASSES of steroid hormones which are involved with reproduction/sexual  behavior and what are specific EXAMPLES of those hormones? androgens: testosterone, dihydrotestosterone, androstenedione estrogens: estradiol gestagens: progesterone hypothalamic hormones: gonadrotropin-releasing hormones (GNRH) gonadotropins: FSH, LH other: prolactin, oxytocin, vasopressin  2. Explain why it is true that the father’s genetic contribution determines the sex of the child?   It is the dad’s haploid sperm which determines the sex of the child.  A child will develop into a  female by default…but the presence of a Y chromosome changes things.  The Y chromosome  has a gene called the Sry gene (sex-determining region).  Around 6 weeks gestation, this gene  secretes a protein which will change the gonads into testes.  Otherwise, the undifferentiated  gonads will develop into ovaries. 3. What hormone(s) determine whether the male or female ductal system will develop? Around 3 months gestation, (if male) the testes will secrete testosterone (to develop Wolffian  ductal system—masculinizing as  well as anti-M llerian substance (to wither away the M llerian ϋ ϋ   ductal system--defeminizing). 4. What hormone(s) determine whether the male or female external genitalia develop? female external genitalia will develop as default dihydrotestosterone will result in male genitalia 5. What part of the primordial gonads eventually becomes the testes?  ovaries? testes: medulla ovaries: cortex
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6. What is androgen insensitivity syndrome and what are the consequences: what does the  external genitalia look like?  what has happened to the ductal systems?  will the person be  sterile or fertile?  is the brain masculinized/defeminized or feminized?  Also, ask me about the  children who grow a penis when they enter puberty. Androgen Insensitivity Syndrome: genetic mutation (on X chromosome) resulting in defective  androgen receptors no masculinization can occur…so external genitalia/body/brain is female no M llerian ductal system, either, however, because the anti- M llerian substance was ϋ ϋ   still secreted sterile brains are feminized 7. What is the persistent m llerian duct syndrome and what are the consequences: what does ϋ   the external genitalia look like?  what has happened to the ductal system?  will the person be  sterile or fertile?  is the brain masculinized/defeminized or feminized?
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