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Integumentary System

Integumentary System - Integumentary System covers entire...

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Integumentary System - covers entire body, responsible for forming discrete barrier from outside, 3 layers Assigned Readings: Chapter 5 – all of it (pp. 138-154) Lecture Outline I. The Skin A. Hypodermis (superficial fascia): subcutaneous connective tissue – deepest layer 1. Mostly adipose tissue fat filled part of skin that gives skin the contour, thickness is variable, skinny vs fat, differences between men and women, men store in belly women in hypodermis, reservoir for energy, some call it part of skin, dermis is intermediate layer 2. Anchors the skin to underlying muscle 3. Acts as a shock absorber and insulator B. Epidermis - on top of dermis, 10 times less thick than dermis 1. Keratinized stratified squamous epithelium 2. Cells of the Epidermis a. Keratinocytes produce a fibrous protective protein called keratin – major cell type that produces keratin – most abundant cell type b. Melanocytes synthesize the pigment melanin – found at bottom of epidermal layer which imparts pigment into our cells c. Langerhans’ cells (epidermal dendritic cells): macrophages that activate immune system moniters for things that may go wrong in epidermis d. Merkel cells are associated with sensory nerve endings – sensory nerve ending that responds to touch 3. Layers of the Epidermis a. Stratum basale (basal layer) – deepest layer – dividing layer between epidermis & dermis, where mitosis takes place and cells move up or stay back to produce more cells
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b. Stratum spinosum (prickly layer) – cells start to connect to each other really well, above basale, some still mitotically active c. Stratum granulosum (granular layer) – start to form granulars inside of them which is a waterproofing agent that will release to outside d. Stratum lucidum (clear layer)
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