chapter 10

chapter 10 - Chapter 10: Metabolism- Biosynthesis Anabolism...

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Chapter 10: Metabolism- Biosynthesis
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Anabolism Energy is used to construct more complex macromolecules/polymers from simpler precursors Most ATP expended for protein synthesis Pathways can be either: Amphibolic: anabolic pathways and catabolic pathways have same the intermediates Usually utilize different enzymes May require different co-factors, energy carriers Strictly anabolic: no common intermediates
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Amino Acid Biosynthesis Many intermediates of catabolic pathways serve as starting points for amino acid biosynthesis: Glycolysis Pentose phosphate shunt TCA cycle Acetyl-CoA itself
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Amino Acid Biosynthesis
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Lipid Biosynthesis Intermediates from glycolysis, as well as acetyl-CoA itself can serve as a starting point for lipids Lipid = fatty acids + glycerol
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Overview of Anabolism
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Nucelotide Biosynthesis Purines and pyrimidines are nitrogenous ring structures synthesized which are synthesized from amino acids Purines stem from amino acids produced from glycolysis intermediate Pyrimidines stem from amino acids produced in the TCA cycle Nucelotides are purines or pyrimidines with an added sugar (ribose or deoxyribose) Riboses are synthesized by the pentose phosphate shunt
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Overview of Anabolism
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Carbohydrate Biosynthesis- NonPhotosynthethic Gluconeogenesis pathway A reversal of glycolysis pathway Begins with a non-carbohydrate source: pyruvate
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chapter 10 - Chapter 10: Metabolism- Biosynthesis Anabolism...

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