chapter 16 -- introduction to viruses

chapter 16 -- introduction to viruses - Chapter 16:...

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Chapter 16: Introduction to Viruses
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Brief History of Viruses Pasteur recognized that rabies was caused by an infectious agent He proposed the term “virus” (poison) Often referred to all infectious agents (incorrectly) as viruses In 1892 Ivanoski isolated the plant pathogen Tobacco Mosaic Virus By 1900 Loeffler & Frosch showed that Hoof-and-Mouth disease in cattle caused by “filterable” agent (porcelain filters) Twort discovered bacterial viruses in 1915
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Novel Properties of Viruses 1. Ultramicroscopic particle Smallest 10-20 nm (poliovirus) About the size of a ribosome Largest 450 nm (poxviruses) Almost as large as small bacteria 2. Compact, economical structure Contain only the bare necessities 3. They do not independently fulfill the characteristics of life: (require a host cell to do these things for them) Growth Metabolism Transport Sensory response Reproduction 4. They exist as inert macromolecules outside their host cells
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Novel Properties of Viruses 5. Many are geometric & can be crystallized
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Novel Properties of Viruses 6. Basic structure consists of protein capsid surrounding nucleic acid Capsid consists of repeating protein subunits 7. Nucleic acid component: can be either RNA or DNA ssDNA ssRNA
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This note was uploaded on 03/24/2009 for the course MIBO 3500 taught by Professor Dustman during the Fall '09 term at University of Georgia Athens.

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chapter 16 -- introduction to viruses - Chapter 16:...

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