stereochemistry - What happens when you have 4 different...

Info icon This preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Stereochemistry What happens when you have 4 different substituents around sp 3 carbon? Non-superimposable mirror images:
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
2 All it takes is… What is happening? plane of symmetry or if you like, a mirror plane
Image of page 2
3 How do we tell the mirror images apart? Absolute configuration How we assign priority: Examples: Absolute configuration? Is this the same molecule or its mirror image? Cl Br F H H F Cl Br And… Absolute Configuration? And… H CH 3 H
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
4 Other ways to depict the molecules: Fischer Projections Rules for manipulating Fischer Projections 1. 90º rotation inverts stereogenic center 2. 180º rotation produces the same molecule 3. Holding one group in place while rotating the other 3 in order produces the same molecule Specific Rotation observed rotation= (specific rotation)x(concentration)x(path length) specific rotation is at the sodium D-line concentration is g/mL path length is in dm [ ] l C D α α =
Image of page 4
5 A single enantiomer is optically pure
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern