What Causes the Membrane Potential?+ve charge outside and –ve charge inside•Large molecules carry a negative charge and neverleave the neuron•More Na+ ion outside more K+ ion inside as a protein called the sodium-potassium transporter lets 3 (Na+) ions out per 2 (K+) ions in.•Protein channels let some ions pass but not other ions to create environments with charges.
Why Does the Membrane Potential Change?Two Primary Forces on Ions1. Diffusion: • The process whereby molecules distribute themselves evenly throughout water• Move from high to low concentrations2. Electrostatic Pressure: The pressure exerted by charges:• like charges repel (+ +) or (- -)• opposite charges attract (+ -)
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