Chp10_cat&inhib

Chp10_cat&inhib - but nevertheless is incredibly...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
To help you distinguish intermediates from a catalyst, consider the following reaction mechanism that describes the most fundamental reaction sequence in enzyme kinetic studies: E + S -> ES ES -> P + E net rxn: S -> P E = enzyme; S = substrate; ES = enzyme-substrate complex; P = product. ES is an intermediate (do you see why? Note the ES is first formed then subsequently consumed within the mechanism). The enzyme, E, is, on the other hand, a catalyst; it is necessarily present as a reactant and is not formed by a prior mechanism step. It is subsequently regenerated in a later step. This simple two-step mechanism forms the basis for vastly more complicated schemes,
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: but nevertheless is incredibly important for understanding biochemical reaction kinetics. This same sequence also forms the basis of almost all petrochemical and polymer catalytic processes - just change the players: S + R -> SR SR -> P + S Where S = catalytic "surface" (e.g. Os, Pt); R = reactant; SR = reactant absorbed onto the catalytic surface; P = product. Note how, in essence, this two-step sequence is identical to the enzyme scheme. Given the economic importance of petrochemicals, drugs, etc., this simple kinetic schema provides the fundamentals of understanding a vast industry of enormous practical impact....
View Full Document

This note was uploaded on 03/29/2009 for the course CH 201 taught by Professor Warren during the Fall '07 term at N.C. State.

Ask a homework question - tutors are online