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Unformatted text preview: enetic material."
- J.D. Watson and F.H.C. Crick Nature (1953) 171: 738
19 Key features of DNA 20 The nitrogenous base
Purines Pyrimidines 21 Chargaff ’s rules ﬁt with X-ray image
Pyrimidine pyrimidine = too small! purine - purine = too bulky! Purine - pyrimidine= JUST RIGHT!
22 DNA vs. RNA (nucleotides) nucleoside = just Sugar and base nucleotide = all Three
23 Nomenclature and the number of phosphates 24 DNA RNA 25 Double stranded RNA Bulge loop Internal loop Multibranched junction Stem loop
26 RNA shape informs function 27 Types of helices
Minor groove Major groove A B Z
The transformation principle Grifﬁth, Avery and co Hershey, Chase and the blender experiment Features of the double helix Watson, Crick and Chargaff Nucleic acid structure (overview) 29 Ungraded problems
Go over Chapter 9: S1 and S3 Try Chapter 9: C4, C8, C12, C13, C20 Try Chapter 9: E1, E5 30 Next Time
Genome organization 31...
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