L12 Short history of DNA

L12 short history of dna

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Unformatted text preview: A short history of the discovery of DNA 1 A short history of the discovery of DNA The transformation principle Griffith, Avery and company Hershey, Chase and the blender experiment Features of the double helix Watson, Crick and Chargaff Nucleic acid structure (overview) 2 What is the genetic material? 1. must carry information 2. must pass from generation from generation 3. must be copied 4. must allow for variation 3 Chromosomes as genetical material Both DNA & protein are present in the nucleus Nuclei divide when cells reproduce Protein - 20 different amino acids allows for more variety than DNA (4 different bases) http://www.stanford.edu/group/pandegroup/folding/education/GAH/chromosomes.jpg 4 DNA structure "We wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.). This structure has novel features which are of considerable biological interest." - J.D. Watson and F.H.C. Crick Nature (1953)171: 738 5 Early evidence of genetic material “the transforming principle” 1928 - Frederick Grif...
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This note was uploaded on 03/29/2009 for the course BIO 325 taught by Professor Saxena during the Fall '08 term at University of Texas at Austin.

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